oral availability

短语

词形变化

oral availabilities 复数 oral availabilities

释义与例句

n.
  1. 1.

    The quality of being efficacious when taken by mouth (usually of a medicinal drug).

    不可数 医学

    2002, Daniel F. Veber, Stephen R. Johnson, Hung-Yuan Cheng, Brian R. Smith, Keith W. Ward, and Kenneth D. Kopple, "Molecular Properties That Influence the Oral Bioavailability of Drug Candidates". Journal of Medicinal Chemistry, 45(12):2615-2623. Retrieved July 9, 2005. An analysis of the measured oral availability in rats for over 1100 compounds studied at SmithKline Beecham has revealed the unexpected positive influence of increasing molecular rigidity as measured by the rotatable bond count and the more expected negative impact of increasing polar surface area.